Saturday, August 10, 2019
Electrophysiology Instramentation and Design Essay
Electrophysiology Instramentation and Design - Essay Example Introduction Many human body organs manifest their body movements through electric activities (Greddes & Baker, 1989). A good example is the heart which produces an electric signal, called an electrocardiogram. In the brain, there is a signal produced called the electroencephalogram (EEG). Eyes produce an electro-oculogram. When these and more other body electrical signals are measured, it becomes possible to measure the pathological functions of the organs (Bonow & Mann 2011). In this paper, there will be an explanation of the state of the art systems and the particular performance motivations that have led to the electrophysiological measurements, their principles of operation, and how they are practically implemented. The article will also look at the role played by engineering in collaboration with synthetic biology and the fundamental essence of automation in the technology. The paper will then be followed by a fundamental look of the recent commercial systems in comparison to t he systems used for research and development. Background: Measurement context and problems The electrophysiological measurements or the bio potentials originate from the electric activities taking place at the cellular levels. ... The separations take place inside and outside the cell. Due to this difference, there is production of a resting potential. There are cells that can be excited resulting to an action potential that can lead to speedy movement of ions across the cell membranes responding to the stimulation of the electricity in the cellââ¬â¢s electric gradient. When the cells are electrically excited, they produce current in the surrounding conducting areas which then manifests itself as the bodyââ¬â¢s potential. There are various bio potentials in human organs (Stober 1986). Physical Background and measurements context The electrophysiological measurements are made feasible through the use of the right materials in design. The designs of the amplifiers should be perfect for acquiring of best quality measurements. Other quality determinant factors are using good electrodes, properly applying them on the patient and good clinical practices. There are various electrodes that can be used for electr ophysiological measurements. Some of the distinguishing features in the electrodes are security, good conduction, less susceptibility to lesser junction potential substances. In order to have a very good contact between the skin and the electrode, an electrode gel is used. When the gels are highly conductive, there is reduction of resistance as well as the junction potential. One of the limitations of using these gels is being that they are causative agents for allergies. Another limitation is the movement of the skin against the electrode, something that causes artefact. Such movements produce motion artifact due to the changing electrode junction to the skin potential. This effect is however reduced through the reduction of movements on unnecessary
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